Friday, February 15, 2019

Alzheimer's and gum

Recent research demonstrated the further relationship between dementia and gum disease bacteria. According to the journal Science Advances, the study discovered the bacteria identified with chronic gum disease known as Porphyromonas gingivalis in the brains of people with Alzheimer’s, which boosted the production amyloid-beta associated with Alzheimer’s. The study progressed to testing new drugs, which are believed to be the basis of a human treatment against Alzheimer’s and are meant to be tested on people later this year.

Friday, February 1, 2019

Leaky blood vessels in the brain may be an early sign of Alzheimer's disease


During recent research, that was recently published in the Nature Medicine journal, was detected that regardless the presence of Alzheimer’s-related protein amyloid and tau older adults with serious memory declines had a high blood vessels leakage. The examination led to the idea of a new drug target for condition prevention, as it could be an early and totally independent process.
The brain tissue is protected by the blood-brain barrier from any damage. The function is destroyed when the vessels stop providing the nutrients and blood flow to the neurons and toxic proteins invade. In other words, were the amyloid or tau pathology present or not, cognitive impairment was still there. Now it is of great value to identify when mental decline starts to take place after damaging the brain blood vessels.