Leaky blood vessels in the brain may be an early sign of Alzheimer's disease

During recent research, that was recently published in the Nature Medicine journal, was detected that regardless the presence of Alzheimer’s-related protein amyloid and tau older adults with serious memory declines had a high blood vessels leakage. The examination led to the idea of a new drug target for condition prevention, as it could be an early and totally independent process.
The brain tissue is protected by the blood-brain barrier from any damage. The function is destroyed when the vessels stop providing the nutrients and blood flow to the neurons and toxic proteins invade. In other words, were the amyloid or tau pathology present or not, cognitive impairment was still there. Now it is of great value to identify when mental decline starts to take place after damaging the brain blood vessels.